Research Article

Protective Effect of Fermented Camel Milk Containing Bifidobacterium longum BB536 on Blood Lipid Profile in Hypercholesterolemic Rats

Table 4

Effect of various fermented types of milk on body weight, blood lipid profile, serum proteins, liver enzymes, and kidney markers in overweight, hypercholesterolemic-made rats on a high-fat, high-cholesterol diet.

Rat groupHF diet onlyHF diet plus
ParameterCCAPCAPCCATCATCT

A. Body weight
BW gain % (13)34.0 ± 1.62a22.35 ± 0.9c20.34 ± 0.3d24.78 ± 0.7b22.3 ± 0.5c26.01 ± 0.8b≤0.00

B. Blood lipid profile
TG mg/dl (46)156.1 ± 4.1a71.5 ± 2.8d80.9 ± 1.7c80.08 ± 2.8c83.3 ± 2.5c98.0 ± 3.3b≤0.00
TC mg/dl (75)142.4 ± 6.0a85.5 ± 2.2e93.1 ± 1.6cd91.27 ± 5.1c98.9 ± 2.26c110.3 ± 3.6b≤0.00
HDL mg/dl (38)27.5 ± 0.41d35.5 ± 2.2ab33.1 ± 1.9bc32.9 ± 0.55bc30.4 ± 2.9cd29.8 ± 1.35cd≤0.006
LDL mg/dl (28)133.7 ± 1.8a35.7 ± 2.7e43.8 ± 1.8d42.6 ± 2.3c41.9 ± 1.7c60.9 ± 1.7b≤0.00
VLDL mg/dl (9)31.27 ± 0.6a14.3 ± 2.7d16.2 ± 0.3c15.32 ± 0.6c16.5 ± 0.4c19.6 ± 0.6b≤0.00

C. Liver function
AST (U/L) (44)115.3 ± 1.6a55 ± 0.73f63.3 ± 0.6e80.3 ± 0.63c65.7 ± 1.0d99.3 ± 0.65b≤0.00
ALT (U/L) (24)60.0 ± 1.0a28.3 ± 0.63f33.9 ± 0.9d32.1 ± 0.7c35.6 ± 0.7c41.7 ± 0.42b≤0.00
Albumin (g/dl) (4)2.95 ± 0.03e4.22 ± 0.14a4.1 ± 0.09ab3.93 ± 0.13bc3.91 ± 0.1bcd3.7 ± 0.02d≤0.00
TP (g/dl) (7)5.48 ± 0.12f7.56 ± 0.08a7.5 ± 0.11ab7.10 ± 0.09de7.31 ± 0.1bc6.9 ± 0.06e≤0.00

D. renal function
Urea (mg/dl) (15)37.89 ± 0.1a19.75 ± 0.26f22.2 ± 0.12e23 ± 0.16d25.1 ± 0.36c27.57 ± 0.3b≤0.00
Creatinine (mg/dl)1.57 ± 0.11a1.05 ± 0.05cd1.07 ± 0.7cd1.11 ± 0.09c1.16 ± 0.12bc1.34 ± 0.11b≤0.001

E. Metabolic syndrome1
Δ MSR (%)0.0005 ± 1.37a−47.5 ± 1.37b−42.46 ± 1.37c−39.11 ± 1.37c−38.66 ± 1.37c−27.69 ± 1.37d≤0.00

1BWG + TG + TC-HDL + VLDL + ALT + AST after normalization of the data.