Effect of a High-Protein High-Fibre Nutritional Supplement on Lipid Profile in Overweight/Obese Adults with Type 2 Diabetes Mellitus: A 24-Week Randomized Controlled Trial

Table 4

Change in blood lipid levels of control and intervention groups over 24 weeks based on intent to treat (n = 65).

Variables	Control group			Intervention group^$			Between-group p value
	Baseline (n = 33)	24 weeks (n = 33)	Within group p value	Baseline (n = 32)	24 weeks (n = 32)	Within group p value
Triglycerides (mg/dL)^a	142 (123–165)	130 (113–150)	0.30	157 (130–188)	152 (122–189)	0.81	0.81
Total cholesterol (mg/dL)	182 ± 41	179 ± 43	0.56	194 ± 46	194 ± 41	0.82	0.58
High-density lipoprotein cholesterol (mg/dL)	40 ± 8	42 ± 10	0.55	39 ± 10	43 ± 10	0.08	0.04
Low-density lipoprotein cholesterol (mg/dL)	111 ± 35	109 ± 37	0.64	123 ± 37	119 ± 36	0.39	0.81
TChol/HDL-ratio	4.6 ± 1	4.4 ± 1.0	0.27	5.0 ± 1.0	4.7 ± 0.9	0.03	0.07

Data presented as TChol/HDL ratio mean ± SD. ^aAntilogarithmic values were presented as mean and 95% CL. Outcome adjusted for baseline (medication count per day), PAL: physical activity level (categorical), gender (category), carbohydrate (g/d), HbA1c (%), energy kcal/d (<,> median), and protein (g/d). value <0.05 considered as significant using the generalized linear model. ^$High-Protein High-Fibre 2 sachets (25 g/sachet in 200 ml water) for 24 weeks.