Effects of Fermented Houttuynia cordata Thunb. on Diabetic Rats Induced by a High-Fat Diet with Streptozotocin and on Insulin Resistance in 3T3-L1 Adipocytes

Table 3

Levels of FBG, FINS, HOMA-IR, and HbA1c.

Metabolic parameter	FBG (mg/dl)	FINS (ng/ml)	HOMA-IR	HbA1c (%)
Normal control	97.3 ± 9.0	3.2 ± 1.2	0.6 ± 0.4	7.8 ± 0.7
HFD control	116.8 ± 5.0	3.9 ± 2.5	1.1 ± 0.8	9.8 ± 0.7
HFD-STZ control	363.0 ± 21.9^++	2.8 ± 0.6	2.5 ± 0.5^+	16.7 ± 1.2^++
HC (10 mg/kg)	300.7 ± 6.5	5.0 ± 2.8	3.7 ± 2.0	16.3 ± 3.3
HC (100 mg/kg)	244.3 ± 54.7	3.34 ± 2.7	2.0 ± 0.9	14.7 ± 2.3
Metformin (100 mg/kg)	305.2 ± 32.3	2.8 ± 2.1	2.1 ± 1.2	16.0 ± 1.3

Results are presented as means ± SD (n = 6 each group). and versus normal control group. and versus HFD-STZ control group. FBG: fasting blood glucose; FINS: fasting serum insulin levels; HOMA-IR: homeostasis model assessment of insulin resistance.