Nanotechnological Strategies for Biofabrication of Human Organs

Figure 3

Nanoparticles. Labeling of cells with nanoparticles for magnetic-driven tissue engineering [3]: (a) Transmission electron micrograph of a typical population of metallic nanoparticles; (b) Light micrograph of human mesenchymal cells derived from bone marrow, which are capable of vascular lineage differentiation. The cells have been labeled with superparamagnetic iron oxide nanoparticles. Staining with Prussian Blue indicates the presence of nanoparticles inside of cells. (c) Transmission electron micrograph of human endothelial cells that were labeled with nanoparticles. White arrows indicate clusters of nanoparticles that had been endocytosed inside the cell.