Nanotechnological Strategies for Biofabrication of Human Organs

Figure 9

Design elements of a clinical robotic bioprinter. (a) Tissue spheroids harvester based on magnetic levitation of tissue spheroids; (b) Principal scheme of clinical robotic bioprinter demonstrating how tissue spheroids can be harvested from multiwells, translocated and dispensed in living tissue using magnetic levitation; (c) Elegant robotic hand developed by group of robotics and mechanotronics at German Aerospace Institute (http://www.dlr.de/rm/en/desktopdefault.aspx/tabid-3803/6175_read-8961/) which can be employed as an essential component in robotic clinical bioprinter for automated nozzle positioning; (d) Computer-aided design of nozzle of clinical robotic bioprinter containing several channels: two channels for fibrinogen and thrombin, one channel for tissue spheroids and additional channel for pressurized air for enabling fibrin hydrogel spraying.