Research Article

Evaluation of Aromatic Boronic Acids as Ligands for Measuring Diabetes Markers on Carbon Nanotube Field-Effect Transistors

Figure 5

Titration of gHSA onto CNT-FET circuits coated with 2 mM pyrene boronic acid. (a) Inhibition of gHSA binding to aromatic boronic acids coated onto CNTs (dark bars) by addition of sorbitol (white bars). (b) 0.1 M MOPS buffer containing 20 mM sorbitol was incubated on the circuits for 30 seconds before addition of 10 μg/mL gHSA containing 20 mM sorbitol, as described in Section 2. Each sample was measured in at least hexuplicate. Unpaired t-test showed significance 𝑃 < 0 . 0 5 for all sorbitol additions.
371487.fig.005a
(a)
371487.fig.005b
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