Tipping the Proteome with Gene-Based Vaccines: Weighing in on the Role of Nanomaterials

Figure 3

Nanoliposome-mediated endocytosis of therapeutic nucleic acids. After escape from the endosome, if the nucleic acid cargo is DNA, then nuclear translocation will occur, permitting the DNA to be transcribed and subsequently translated. If the nucleic acid cargo is RNA, it is translated in the cytoplasm.