Figure 2: Size measurement by dynamic light scattering. (a) SiNPs that are not amino-functionalized (without APTES), (b) SiNPs that are amino-functionalized (with APTES), and (c) SiNPs-CLN4 (amino-functionalized nanoparticles conjugated to anti-Claudin-4). Measurement of zeta potential (surface charge) of (d) SiNPs (not amino-functionalized) and (e) SiNPs amino-functionalized. (f) Transmission electron microscope image showing the size and morphology of SiNPs encapsulating doxorubicin and conjugated to CLN4. nm: diameter in nanometers.