Cyclosporine A Loaded PLGA Nanoparticles for Dry Eye Disease: In Vitro Characterization Studies

Table 3

Results of analysis of variance for particle size.

Parameters	DF*	SS*	MS*	𝐹^∗	Significance of  P
Particle size
Model	2	1161.1	5806.5	5.53	0.0434 significant
Residual	6	6295.87	1049.3	—	—
Total	8	17908.98	—	—	—
Zeta potential
Model	5	132.79	26.56	29.34	0.0095 significant
Residual	3	2.72	0.91	—	—
Total	8	135.51	—	—	—

Where, DF* indicates degrees of freedom; SS* sum of square; MS* mean sum of square and 𝐹^∗ is Fischer’s ratio.