Cyclosporine A Loaded PLGA Nanoparticles for Dry Eye Disease: In Vitro Characterization Studies

Table 6

Model fitting of the release profile using four different models.

Batch code	Coefficient of determination (𝑅^2)			Best fit model
	Zero order	First order	Higuchi
F3	0.909	0.893	0.974	Higuchi
Korsmeyer Peppa's equation
	𝑅^2	𝐾 value	𝑁 value	Mechanism
F3	0.977	0.316	0.508	Quasi fickian

The bold values refer to coefficient of variation and its correct according to given headings.