Particle Size Affects Concentration-Dependent Cytotoxicity of Chitosan Nanoparticles towards Mouse Hematopoietic Stem Cells

Table 1

Effects of autoclaving process and chitosan concentrations on particle size and zeta potential of CSNPs prepared from MMW chitosan, .

Chitosan; concentrations (w/v)	Before autoclaving		After autoclaving
	Particle size (nm ± SD)	Zeta potential (mV ± SD)	Particle size (nm ± SD)	Zeta potential (mV ± SD)
0.2	490.7 ± 99.2	+54.3 ± 0.3	712.1 ± 56.8	+55.9 ± 3.7
0.3	826.3 ± 75.9	+56.6 ± 1.4	1363.3 ± 95.6	+62.0 ± 1.9
0.4	1413.7 ± 12.3	+64.5 ± 0.5	1406.7 ± 75.0	+61.5 ± 2.7
0.5	1979.5 ± 89.5	+63.7 ± 2.3	1556.3 ± 146.9	+62.3 ± 2.9
0.6	2195.7 ± 40.4	+66.7 ± 5.5	1756.3 ± 47.1	+60.1 ± 4.0