Plant-Mediated Green Synthesis of Ag NPs and Their Possible Applications: A Critical Review

Table 4

Morphology of green synthesized Ag NPs and their anti-inflammatory activity on different inflammation models.

Size by TEM/SEM with morphology	Inflammation model	%inhibition/IC50/binding constant	Reference
SEM 32–38 nm size with spherical shape	BSA protein	Binding constant (2.01 ± 0.06) × 10–4	[152]
TEM 15–20 nm size with spherical shape	BSA protein	IC50: 84 μM	[6]
—	Protein inhibitory activity	89.17 + 1.4%	[153]
	Albumin denaturation	84.64 + 1.4%
	Membrane stabilization	84.18 + 1.4%
TEM 25 nm average size with spherical shape	HaCaT cells	IL-1α-55%	[154]
		IL-1β-69%
		IL-6-68%
TEM 20–80 nm size with spherical shape	HaCaT cells	IL-1α-49%	[155]
		IL-1β-92%
		IL-6-74%