Green Synthesis of Silver Nanoparticles Using Extracts of Ehretia cymosa and Evaluation of Its Antibacterial Activity in Cream and Ointment Drug Delivery Systems

Table 3

pH and spreading time of cream formulations.

Formulations	pH	Spreading time (sec)
CB	5.4 ± 0.12	18.2 ± 2.22
ACC1	5.6 ± 0.65	17.9 ± 0.78
ACC2	5.8 ± 0.02	16.3 ± 1.47
ACC3	5.9 ± 0.00	14.0 ± 3.05
MCC1	5.5 ± 0.14	14.3 ± 1.63
MCC2	5.9 ± 0.07	13.7 ± 0.80
MCC3	5.7 ± 0.02	11.7 ± 0.14
ASC1	6.2 ± 0.16	11.4 ± 4.42
ASC2	6.0 ± 0.30	10.8 ± 3.07
ASC3	5.8 ± 0.05	9.5 ± 5.71
MSC1	5.9 ± 0.08	9.3 ± 2.22
MSC2	5.6 ± 0.21	8.9 ± 2.80
MSC3	5.2 ± 0.10	7.6 ± 0.09
CC	6.4 ± 0.62	13.5 ± 1.63

Note. CB: cream base (negative control), ACC1, ACC2, and ACC3: 1%, 1.5%, and 2% aqueous crude extract cream, respectively, MCC1, MCC2, and MCC3: 1%, 1.5%, and 2% methanol crude extract cream, respectively, ASC1, ASC2, and ASC3: 1%, 1.5%, and 2% aqueous SNPs cream, respectively, MSC1, MSC2, and MSC3: 1%, 1.5%, and 2% methanol SNPs cream, respectively, and CC: 1% ciprofloxacin cream (positive control).