Dexamethasone-Loaded Pseudo-Protein Nanoparticles for Ocular Drug Delivery: Evaluation of Drug Encapsulation Efficiency and Drug Release

Table 2

Main characteristics of the freshly prepared DEX-NPs with different concentrations of DEX.

DEX content (wt% of the polymer)	AD (nm) ± SD	PDI ± SD	ZP (mV) ± SD
10	143.6 ± 0.8	0.069 ± 0.010	−26.6 ± 1.4
20	151.8 ± 0.3	0.098 ± 0.025	−31.5 ± 3.2
30	155.2 ± 4.6	0.065 ± 0.034	−26.3 ± 1.7
40	156.9 ± 2.0	0.102 ± 0.017	−28.4 ± 2.7
50	164.1 ± 9.5^§	0.272 ± 0.074^§	−16.3 ± 0.8^§

AD, average diameter; PDI, polydispersity index; ZP, zeta-potential; SD, standard deviation. ^§Partially aggregated sample. Data presented are averages of three independent experiments.