Dexamethasone-Loaded Pseudo-Protein Nanoparticles for Ocular Drug Delivery: Evaluation of Drug Encapsulation Efficiency and Drug Release

Table 3

Drug incorporation characteristics of the DEX-NPs.

DEX content (wt% of the polymer)	EE (%) ± SD	DL (%) ± SD	Stability of DEX-NPsupon storage at 4°C
10	25.9 ± 0.4	2.5 ± 0.3	Stable
20	55.1 ± 1.1	10.2 ± 0.3	Stable
30	62.8 ± 5.0	15.8 ± 1.1	Partial aggregation within a week
40	58.9 ± 2.8	19.0 ± 0.7	Partial aggregation within a week
50	18.0 ± 1.2	8.2 ± 0.4	Partial aggregation during the preparation

EE, encapsulation efficiency; DL, drug loading; SD, standard deviation. Data presented are averages of three independent experiments.