Dexamethasone-Loaded Pseudo-Protein Nanoparticles for Ocular Drug Delivery: Evaluation of Drug Encapsulation Efficiency and Drug Release

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Sample</td><td class="align_center" colspan="4">Measurement time</td></tr><tr class="thead"><td class="align_center">Freshly prepared</td><td class="align_center">After 1 month</td><td class="align_center">After 3 months</td><td class="align_center">After 6 months</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_center" colspan="5">AD (nm) ± SD<br/>[PDI ± SD]</td></tr><tr><td class="align_left" colspan="5"><hr/></td></tr><tr><td class="align_left">DEX-NPs</td><td class="align_center"><b>151.8</b> ± <b>0.3</b> [0.098 ± 0.025]</td><td class="align_center"><b>151.9</b> ± <b>1.9</b> [0.089 ± 0.022]</td><td class="align_center"><b>153.2</b> ± <b>0.2</b> [0.103 ± 0.022]</td><td class="align_center"><b>157.0</b> ± <b>0.8</b> [0.107 ± 0.049]</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>AD, average diameter; PDI, polydispersity index; SD, standard deviation. Data presented are averages of three independent experiments. The average diameters of the NPs are given in bold.<br/></div></td></tr></table>

<div>Stability of the prepared DEX-NPs upon storage at 4°C.</div>

Journal of Nanotechnology

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Table 4

Table 4: Dexamethasone-Loaded Pseudo-Protein Nanoparticles for Ocular Drug Delivery: Evaluation of Drug Encapsulation Efficiency and Drug Release 