Research Article

Radiation Therapy in Addition to Gross Total Resection of Retroperitoneal Sarcoma Results in Prolonged Survival: Results from a Single Institutional Study

Table 1

Patient and tumor characteristics (all patients).

ParameterNo. of patients (%)

Sex

Male11 (35%)
Female20 (65%)

Age (range) 56 (20–83)

Race

Caucasian28 (90%)
African American3 (10%)

History of tobacco use 11 (35%)

Family history of malignancy 7 (23%)

Breast cancer4 (13%)
Breast and ovarian cancers2 (6%)
Sarcoma1 (3%)

Prior cancer 4 (13%)

Breast1 (3%)
Melanoma1 (3%)
Hodgkin’s disease1 (3%)

Prior radiation 3 (10%)

TNM stage

T2bN0M025 (81%)
T2bN0M14 (13%)
Desmoid2 (6%)

Grade

16 (19%)
26 (19%)
317 (55%)

AJCC stage

I10 (32%)
III15 (48%)
IV4 (13%)

Recurrent RPS 7 (23%)

Pretreatment size of RPS (range) 10.5 cm ( )

Histology

Leiomyosarcoma15 (48%)
Liposarcoma10 (32%)
Myxoid3 (10%)
Dedifferentiated4 (13%)
Desmoid2 (6%)
Malignant fibrous histiocytoma3 (10%)
Inflammatory myofibroblastic sarcoma1 (3%)

CD 117 staining

Not done16 (52%)
Negative10 (32%)
Positive5 (16%)
Imatinib mesylate given1 (3%)

Symptoms at presentation

Pain/discomfort20 (65%)
Weight loss (range)9 (31%) 10–30 lbs
Early satiety/decreased appetite6 (21%)
Nausea3 (10%)
Change in menses2 (7%)
Small bowel obstruction2 (7%)