Journal of Oncology / 2008 / Article / Tab 4

Research Article

Radiation Therapy in Addition to Gross Total Resection of Retroperitoneal Sarcoma Results in Prolonged Survival: Results from a Single Institutional Study

Table 4

RTOG acute and late toxicities of radiation.

ParametersPreoperative EBRT group Postoperative EBRT group P value

Acute ( 90 days)

GI

Grade 1-216 (84%)11 (92%) .70
Grade 3-41 (5%)0 (0%)

GU

Grade 1-20 (0%)3 (25%) .05
Grade 3-40 (0%)0 (0%)

Wound complications

Grade 1-20 (0%)1 (8%) .39
Grade 3-40 (0%)0 (0%)

Infection

Grade 1-20 (0%)0 (0%) 1.00
Grade 3-41 (5%)0 (0%)

Skin

Grade 1-22 (11%)1 (8%) 1.00
Grade 3-40 (0%)0 (0%)

Pain

Grade 1-211 (58%)5 (42%) .47
Grade 3-40 (0%)0 (0%)

Neurologic

Grade 1-22 (11%)0 (0%) .51
Grade 3-40 (0%)0 (0%)

Gynecologic

Grade 1-20 (0%)0 (0%) 1.00
Grade 3-41 (5%)0 (0%)

Late ( 90 days)

GI

Grade 1-21 (5%)2 (17%) .51
Grade 3-43 (16%)3 (25%)

GU

Grade 1-20 (0%)0 (0%) 1.00
Grade 3-41 (5%)0 (0%)

Wound complications

Grade 1-20 (0%)0 (0%) 1.00
Grade 3-41 (5%)0 (0%)

Infection

Grade 1-20 (0%)0 (0%) .31
Grade 3-44 (21%)2 (17%)

Skin

Grade 1-20 (0%)0 (0%)NS
Grade 3-40 (0%)0 (0%)

Pain

Grade 1-21 (5%)0 (0%) 1.00
Grade 3-40 (0%)0 (0%)

Neurologic

Grade 1-21 (5%)0 (0%) 1.00
Grade 3-40 (0%)0 (0%)

Gynecologic

Grade 1-20 (0%)0 (0%) 1.00
Grade 3-42 (11%)1 (8%)

Lymphedema

Grade 1-21 (5%)0 (0%) 1.00
Grade 3-40 (0%)0 (0%)

RTOG = Radiation therapy oncology group; EBRT = external beam radiation therapy; GI = gastrointestinal; GU = genitourinary.

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