Biochanin A Modulates Cell Viability, Invasion, and Growth Promoting Signaling Pathways in HER-2-Positive Breast Cancer Cells
Figure 1
Effect of biochanin A on MCF-10A, NIH-3T3, and SK-BR-3 cell viability. SK-BR-3/NIH-3T3 and MCF-10A cells were seeded at 2000 and 5000 cells/well in a 96-well plate. After 8 hours of cell adhesion period, the cells were treated with biochanin A (2–100 M) for 72 hours. The data indicate a biphasic effect of biochanin A on SK-BR-3 breast cancer cell viability. Biochanin A did not inhibit MCF-10A and NIH-3T3 cell viability. C: control or no treatment; DMSO: vehicle (Statistical analysis: One-way Anova, , *).
