Biochanin A Modulates Cell Viability, Invasion, and Growth Promoting Signaling Pathways in HER-2-Positive Breast Cancer Cells
Figure 8
Effect of biochanin A on MT-MMP1 protein expression. (a) SK-BR-3 breast cancer cells were seeded in a T-75 flask in RPMI-1640 cell culture media (10% FBS). Following 72 hours of treatment with biochanin A (2–50 M) MT-MMP1 protein expression was evaluated. Our data indicate reduced MT-MMP-1 expression at 10 and 50 M biochanin A (Biochanin A: 10 M ; 50 M ; ). C: control or no treatment; DMSO: vehicle (Statistical analysis: One-way Anova, , *). (b) Representative blot for MT-MMP-1 protein expression.
