List of miRNAs and their target gene involved in human breast cancer.
|MicroRNA||Targets||Aberrant expression and roles||References|
|MiR-21||BCL2, TPM1, PDCD4, PTEN||Overexpressed and play oncogenic role||[14–17]|
|MiR-10b||Homeobox D10||Down modulated, but associated with metastatic potential|||
|MiR-27a||ZBTB10||Oncogenic role in breast cancer cells|||
|MiR-17-5p||AIB1||Oncosuppressor in breast cell lines|||
|MiR-125a, miR-125b||ERBB2, ERBB3||Down modulated and act as oncosuppressor||[9, 25]|
|Let-7||RAS, HMGA2||Down modulated and reduced in BT-ICs|||