Journal of Oncology / 2009 / Article / Tab 5

Research Article

A Population-Based Clinical Trial of Irinotecan and Carboplatin

Table 5

Comparison of features of population based versus modified-Fibonacci method in phase I trials.

FeaturesPopulation basedFibonacci

Number of patients required~50~20
Enrollment of patientsContinuousCohorts of three
Waiting time between cohortsNoneRequired
Efficacy optimized YesNo
Preliminary efficacy dataYesYes/No

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.