Journal of Oncology / 2009 / Article / Fig 3

Research Article

Modulation of CXCR4, CXCL12, and Tumor Cell Invasion Potential In Vitro by Phytochemicals

Figure 3

In combination, genistein and DIM are more efficacious in the downregulation of CXCR4 and CXCL12 mRNAs than either compound alone. The effect of downregulation of CXCR4 in (a) MDA-MB-231 and (b) BG-1 cells by 20  M DIM and 100  M genistein in combination is greater than their individual effects. The same is seen in (b) BG-1 cells after CXCL12 quantification. Ctl = DMSO alone; , .
491985.fig.003a
(a) MDA-MB-231
491985.fig.003b
(b) BG-1

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.