Circulating Vitamin D and Risk of Epithelial Ovarian Cancer
Table 2
Circulating 25(OH)D levels by baseline characteristics, NYUWHS and NSHDS controls.
Characteristi
25(OH)D by Cohort (nmol/L)
NYUWHS
NSHDS
Median
(25%–75%)
Median
(25%–75%)
Age at sampling, y
≤50 years
42
40.5
(24.6–64.0)
91
37.5
(24.1–53.8)
50–60 years
46
45.9
(30.7–66.7)
71
43.7
(28.4–68.1)
60 years
35
44.9
(36.0–59.7)
29
39.4
(33.4–58.9)
P-trend (continuous)
.15
.007
BMI at enrollment, kg/cm2
25
60
51.6
(31.3–67.2)
89
43.4
(29.7–65.8)
25–29
39
43.4
(29.7–53.8)
69
35.8
(24.1–50.2)
≥30
21
32.0
(25.5–44.6)
26
38.3
(24.8–61.0)
P-trend (continuous)
.004
.05
Menopausal status at enrollment
Premenopausal
51
37.5
(25.1–63.6)
53
34.8
(23.4–49.5)
Postmenopausal
72
45.6
(32.7–67.2)
138
42.2
(28.1–65.8)
P-value
.03
.002
Parity
Never
39
41.9
(29.7–65.8)
19
35.8
(21.9–53.4)
Ever
84
45.6
(29.4–64.0)
153
39.7
(25.6–61.8)
P-value
.49
.14
Oral contraceptives use
Never
62
44.6
(30.9–68.1)
89
38.6
(24.8–61.0)
Ever
28
49.5
(30.1–61.4)
74
42.5
(24.8–62.2)
P-value
.46
.67
Smoking status
Never
37
45.9
(30.7–61.4)
100
40.8
(26.7–64.0)
Former
39
44.6
(31.6–66.7)
40
38.1
(25.5–60.1)
Current
20
49.9
(27.9–66.3)
36
37.5
(22.0–54.9)
P-value
.62
.12
Season
Jan–Mar
29
38.1
(26.7–45.9)
63
34.1
(24.1–58.9)
Apr–Jun
26
42.5
(26.2–53.8)
44
40.8
(29.2–60.1)
Jul–Sep
40
49.9
(30.7–69.1)
16
46.2
(35.8–62.2)
Oct–Dec
28
55.7
(34.3–65.3)
68
43.4
(24.3–62.2)
P-value
.13
.02
ll variables had missing data for fewer than 7 controls except for NHSDS: parity (19 missing), oral contraceptives use (28 missing), and smoking (15 missing), and for NYUWHS: oral contraceptives use (33 missing) and smoking (27 missing).
