TJ-41 Induces Apoptosis and Potentiates the Apoptotic Effects of 5-FU in Breast Cancer Cell Lines

Figure 3

Cell cycle kinetics of BrCa cells after treatment with TJ-41 and 5-FU. MCF-7 and MDA-MB-231 cells were treated with TJ-41 and 5-FU either alone or combined for 48 hours. DNA was stained with propidium iodide. The figure shows the cell cycle profile of control cells (a) and (e), TJ-41-treated cells (b) and (f), 5-FU treated cell (c) and (g), and TJ-41 and 5-FU combined (d) and (h). Results are from one experiment that is representative of three similar ones.