A Combination of Systemic and Intracranial Anti-CD25 Immunotherapy Elicits a Long-Time Survival in Murine Model of Glioma

<table>Effect of anti-CD25 mAb immunotherapy on TILs of glioma-bearing mice. (a) FACS dot plot of TILs analyzed by CD4 and CD8 double staining. (b) Distribution of CD4<sup>+</sup> and CD8<sup>+</sup> T cells within context of anti-CD25 glioma immunotherapy, compared between brain and bone marrow. Data are presented as the percentage average of cells and represent the mean of three individual experiments (<svg height="11.375" id="M46" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Journal of Oncology

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Figure 4

Figure 4: A Combination of Systemic and Intracranial Anti-CD25 Immunotherapy Elicits a Long-Time Survival in Murine Model of Glioma 