Review Article
PAI-1 Regulates the Invasive Phenotype in Human Cutaneous Squamous Cell Carcinoma
Table 1
Transcript levels for select Cancer Pathway genes.
| | Gene name | Symbol | Quiescent versus TGF-β1+EGF |
| | Angiopoietin 1 | ANGPT1 | 3.01 | | Breast cancer 1, early onset | BRCA1 | | | Cyclin-dependent kinase 2 | CDK2 | 2.46 | | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | CDKN1A | 7.41 | | Interferon α1 | IFNα1 | 5.66 | | Interferon β1, fibroblast | IFNβ1 | 6.87 | | Integrin α1 | ITGα1 | 5.66 | | Integrin α2 | ITGα2 | 18.25 | | Integrin β1 | ITGβ1 | 11.71 | | Integrin β3 | ITGβ3 | 59.30 | | Integrin β5 | ITGβ5 | 5.82 | | Matrix metallopeptidase 1 | MMP1 | 59.30 | | Matrix metallopeptidase 9 | MMP9 | 55.33 | | Metastasis associated 1 | MTA1 | 2.19 | | Metastasis associated 1 family, member 2 | MTA2 | 1.82 | | Metastasis suppressor 1 | MTSS1 | 5.58 | | Platelet-derived growth factor β polypeptide | PDGFB | 9.51 | | Plasminogen activator, urokinase | PLAU | 2.64 | | Plasminogen activator, urokinase receptor | PLAUR | 8.00 | | Serpin peptidase inhibitor, clade E (plasminogen activator inhibitor-1) | SERPINE1 | 168.90 | | Transforming growth factor β1 | TGFβ1 | 5.54 | | Transforming growth factor β receptor 1 | TGF-βR1 | 3.46 | | Thrombospondin 1 | THBS1 | 9.25 | | Tumor necrosis factor receptor superfamily, member 10b | TNFRSF10B | 2.16 | | Tumor necrosis factor receptor superfamily, member 25 | TNFRSF25 | 3.53 | | Vascular endothelial growth factor A | VEGFA | 23.26 |
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