MicroRNA as a Novel Modulator in Head and Neck Squamous Carcinoma

Table 2

Antecedent studies identified microRNA expression level change in head and neck cancer.

miRNA	Up-regulated	Down-regulated	Study groups/methods	References
let7i; 15a; 15b; 17a; 18; 18a; 18b; pre 21; 21; 21-17p; 24-1p; 98; 99b; 104; 126; 130b; 137; 140; 142-3p; 146; 146b; 151; 152; 155; 181b; 181d; 184; 188; 192; 193b; 199b-2p; pre-205; 213; 301; 325; 333; 337; 338; 374; 455; 491	v			[61, 102, 113–115, 161–167]
let-a family; let-7 family; let7a; 10b; 20b; 23 family; 27 family; 30; 34 family; 34c; 93-7p; 99a; 100; 107; 125; 125a; 127; 144; 154; 195; 200 family; 200a; 291-3p; 368; 370; 378; 422 family; 494		v		[61, 102, 113, 114, 119, 162, 164–168]
9	v		13 NPC/real time-PCR	[162]
		v	18 OC cell lines/real-time-PCR	[164]
16	v		9 HNSCC cell lines/Microarray	[113]
		v	31 NPC/real time-PCR	[166]
17	v		13 NPC/real time-PCR	[162]
		v	31 NPC/real time-PCR	[166]
23b	v		104 HNSCC/Microarray and real time-PCR	[102]
		v	5 SCC/real time-PCR	[165]
29c	v		4 HNSCC/Microarray	[114]
		v	31 NPC/real time-PCR	[166]
31	v		18 OC cell lines/real time-PCR	[164]
		v	13 NPC/real time-PCR	[162]
34b	v		5 SCC/real time-PCR	[165]
		v	13 NPC/real time-PCR	[162, 166]
			31 NPC/real time-PCR
138	v		13 NPC/real time-PCR	[162]
		v	4 OSCC/real time-PCR	[61]
221	v		99 HNSCC and 14 normal/Microarray and real time-PCR	[115, 165]
			5 SCC/real time-PCR
		v	31 NPC/real time-PCR	[166]
340	v		18 OC cell lines/real time-PCR	[164]
		v	9 HNSCC cell lines/Microarray	[113]
375	v		169 HNSCC/real time-PCR	[161]
		v	99 HNSCC and 14 normal/Microarray and real time-PCR	[115, 167]
16 pleomorphic adenoma/Microarray and real time-PCR
449	v		16 pleomorphic adenoma/Microarray and real time-PCR	[167]
		v	9 HNSCC cell lines/Microarray	[113]

MiRNA: microRNA; NPC: nasopharyngeal carcinoma; OC: oral cancer; HNSCC: head and neck squamous cell carcinoma; SCC: squamous cell carcinoma.