Research Article

Expression of Chemoresistance-Related Genes and Heat Shock Protein 72 in Hyperthermic Isolated Limb Perfusion of Malignant Melanoma: An Experimental Study

Table 1

Group I ( 𝑛 = 1 2 ). Gene expression by variation of perfusion time at normothermic conditions without cytostatic drug (gene expression/number of tumor samples).

Untreated tumorPerfusion time (minutes)
30609060 + 5 hours

Gene
mdr13/33/33/33/33/3
mrp13/33/32/33/32/3
mrp20/30/30/30/30/3
lrp3/33/33/33/33/3