Use of H19 Gene Regulatory Sequences in DNA-Based Therapy for Pancreatic Cancer
Figure 1
ISH of well-differentiated pancreatic carcinoma from two different patients. (a) Detection of H19 transcript using Dig-labeled H19 LNA-DNA probe by ISH. The arrow points to the positive hybridization signals within the cytoplasm of the cancer cells (10X magnification). (b) Detection of H19 transcript using Dig-labeled H19 LNA-DNA probe by ISH. The arrow points to the positive hybridization signals within the cytoplasm of the cancer cells (20X magnification). Tissue was later stained using Hematoxylin and Eosine.