Journal of Oncology / 2010 / Article / Tab 1

Research Article

Repeated Intraperitoneal 𝛼 -Radioimmunotherapy of Ovarian Cancer in Mice

Table 1

Study groups and number of mice with macroscopic and microscopic tumors and ascites.

GroupnTreatmentNumber of treatmentsMacroscopic tumorsMicroscopic tumorsAscites T F F

118 4 0 0 k B q 2 1 1 A t -MX35 F ( a b ) 2 in P B S 111/1815/1815/180.17
218 4 0 0 k B q 2 1 1 A t -MX35 F ( a b ) 2 in P B S 216/1816/188/180.11
318 4 0 0 k B q 2 1 1 A t -MX35 F ( a b ) 2 in PBS311/1811/185/180.39
418 4 0 0 k B q 2 1 1 A t -MX35 F ( a b ) 2 in P B S 410/1810/181/180.44
518 4 0 0 k B q 2 1 1 A t -MX35 F ( a b ) 2 in P B S 510/1810/180/180.44
618 4 0 0 k B q 2 1 1 A t -MX35 F ( a b ) 2 in P B S 66/186/180/180.67
712MX35 F ( a b ) 2 in PBS112/1212/1210/120

T F F tumor-free fraction (i.e., fraction of animals with no macro- and microscopic tumors and no ascites). Injected activities were 4 0 0 ± 14 kBq (mean ± SEM). P B S phosphate-buffered saline. The presence of macroscopic tumors and ascites was assesed by careful ocular inspection during dissection 2 mo after the last administration of the radioimmunocomplex. Microscopic tumor growth was assessed by conventional histopathology. Judgements were blinded from treatment information.