Research Article

Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV

Figure 4

Effect of SKI-606 and Iressa on colony formation ability of HeLa cell line. HeLa cells are able to form large colonies in soft agar. In contrast, SKI-606 inhibits the colony formation ability of HeLa ( 𝑃 < . 0 0 0 1 ) and SiHa cells (data not shown) in soft agar, whereas, Iressa slightly reduce the colony formation following treatment with 5  𝜇 M as described in the Materials and Methods section. Magnification is 100x. We have obtained the same results using SiHa cell line.
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