Thrombospondin-1 (TSP-1) Stimulates Expression of Integrin 6 in Human Breast Carcinoma Cells: A Downstream Modulator of TSP-1-Induced Cellular Adhesion
Figure 7
High endogenous TSP-1 production increases cell invasion of laminin. Tumor cell invasion of laminin was performed as described in Section 2. Invasion of cells untreated (a), invasion of cells pretreated with either with either 10 g/mL control IgG or 10 g/mL goat antihuman TSP-1 IgG or 10 g/mL rat antihuman 6 integrin IgG (b). The error bars represent the standard error of the mean of triplicate samples and the experiment was repeated three times with similar results.
