Role of Angiopoietin-2 in Regulating Growth and Vascularity of Astrocytomas

Table 2

Effect of Ang2 on intracranial U87MG xenografts.

	U87MG:Ctl	U87MG:Ang2
		no. Dox.	1 mg/mL Dox	10 mg/mL Dox
	𝑛 = 10	𝑛 = 10	𝑛 = 10	𝑛 = 10
Overall survival (days)	63.7	54.7*	71.7*	74.4
	(SEM = 2.3)	(SEM = 3.3)	(SEM = 2.3)	(SEM = 3.5)
		𝑃=.015	𝑃=.021	𝑃=.0149
Proliferation index	0.043	0.094*	0.038*	0.035*
	(SEM = 0.01)	(SEM = 0.01)	(SEM = 0.00)	(SEM = 0.00)
		𝑃=.0039	𝑃=.3989	𝑃=.4262
MVD (vessels/HPF) mean of 10 counts	5.8	8.8*	4.6*	4.0*
	(SEM = 0.478)	(SEM = 0.859)	(SEM = 0.616)	(SEM = 0.785)
		𝑃=.0132	𝑃=.038	𝑃=.0189