Journal of Oncology / 2010 / Article / Tab 1

Research Article

Significant Growth Inhibition of Canine Mammary Carcinoma Xenografts following Treatment with Oncolytic Vaccinia Virus GLV-1h68

Table 1

Viral titer in tissue samples (pfu/organ or tumor).

Animal no./dpi1/21 dpi2/21 dpi3/21 dpi4/42 dpi5/42 dpi

Liver1201716840n.dn.d
Lungs1520480n.d.56324
Kidneysn.d.n.d.n.d.NTNT
Spleen150n.dn.dn.dn.d
Ovariesn.d.n.d30NTNT
Tumor2×1071×1072.1×1077.3×1057.3×105

Tumor-bearing mice were injected with 5×106 pfu of GLV-1h68. Mice were sacrificed at day 21 or 42 after virus injection (dpi). The data were determined by standard plaque assays on CV-1 cells using aliquots of the homogenized organs and were displayed as mean pfu/organ or tissue. For each organ, two aliquots of 0.1 ml were measured in triplicates.
n.d.: not detected (detection LIMIT<10 pfu/organ).
NT: not tested.

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