Association of ABCC2 and CDDP-Resistance in Two Sublines Resistant to CDDP Derived from a Human Nasopharyngeal Carcinoma Cell Line

Table 2

Relative quantification of four ABC transporters.

ABC transporters	CNE2	CNE2-CDDP		CNE2-CDDP-5Fu
	$\mathrm{\Delta }$Ct	$\mathrm{\Delta }$Ct	Fold change ($2^{-\mathrm{\Delta }\mathrm{\Delta }\text{Ct}}$)	$\mathrm{\Delta }$Ct	Fold change ($2^{-\mathrm{\Delta }\mathrm{\Delta }\text{Ct}}$)
ABCB1	22.6 ± 0.3	22.8 ± 0.5	0.87	22.2 ± 0.5	1.32
ABCC1	12.8 ± 0.2	13.3 ± 0.2	0.71	14.1 ± 0.1	0.41
ABCC2	10.9 ± 0.1	9.6 ± 0.1${}^{*}$	2.46	8.8 ± 0.1${}^{*}$	4.29
ABCG2	16.2 ± 0.2	16.0 ± 0.6	1.15	14.8 ± 0.5${}^{*}$	2.64

${}^{*}$ P  <  .05 versus CNE2.