Breast Carcinoma Cells in Primary Tumors and Effusions Have Different Gene Array Profiles

Figure 5

The prognostic role of p130cas expression in breast carcinoma effusions. (a): Kaplan-Meier survival curve showing the trend for association between p130cas expression and overall survival (OS) for 44 patients with breast carcinoma effusions. Patients with effusions with higher expression ($>$25% of tumor cells) ($n=33$, dashed line) had a mean OS of 78 months versus 142 months for patients whose effusions showed low ($\le$25%) expression ($n=11$, solid line; $P=.062$). (b): Kaplan-Meier survival curve showing the trend for association between p130cas expression and disease-free survival (DFS) for 42 patients with breast carcinoma effusions. Patients with effusions with higher expression ($>$25% of tumor cells) ($n=31$, dashed line) had a mean DFS of 48 months versus 89 months for patients whose effusions showed low ($\le$25%) expression ($n=11$, solid line; $P=.098$). DFS data were unavailable for 2 patients.

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