Breast Carcinoma Cells in Primary Tumors and Effusions Have Different Gene Array Profiles

Table 1

Selected genes identified by fold-change analysis using the MATLAB R2007a program that are differentially expressed in primary tumors versus effusions (complete list available in supplementary Table  1).

Genes more highly expressed in effusions
Gene	Full name	Log2 change
CLDN4	Claudin-4	4.8544
KRT8	Keratin 8	3.9099
NTN4	Netrin-4	3.5957
VIL2	Villin 2	2.7965
FASN	Fatty acid synthase	2.7583
DLX3	Distal-less homeobox 3	2.3846
ZNF75C	ZNF75C	2.2346
TRAF4	TNF-receptor-associated factor 4	2.0682
NEDD4L	Neural precursor cell expressed, developmentally down-regulated	2.0061
NPC1L1	NPC1 (Niemann-Pick disease, type C1 gene)-like 1	1.9928
Genes more highly expressed in primary tumors
CLDN19	Claudin-19	20.4327
HPR	Haptoglobin-related protein	11.7846
IGFBP7	Insulin-like growth factor binding protein 7	10.6376
ZFYVE20	Zinc finger FYVE domain containing 20	10.4542
HP	Haptoglobin	9.1384
GFRA1	GDNF family receptor alpha 1	8.6866
APOBEC2	Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	8.6565
STK39	Serine threonine kinase 39 (STE20/SPS1 homolog, yeast)	8.0239
SLC6A16	Solute carrier family 6, member 16	7.2568