Table 1: Selected genes identified by fold-change analysis using the MATLAB R2007a program that are differentially expressed in primary tumors versus effusions (complete list available in supplementary Table  1).

Genes more highly expressed in effusions

GeneFull nameLog2 change
CLDN4Claudin-44.8544
KRT8Keratin 83.9099
NTN4Netrin-43.5957
VIL2Villin 22.7965
FASNFatty acid synthase2.7583
DLX3Distal-less homeobox 32.3846
ZNF75CZNF75C2.2346
TRAF4TNF-receptor-associated factor 42.0682
NEDD4LNeural precursor cell expressed, developmentally down-regulated2.0061
NPC1L1NPC1 (Niemann-Pick disease, type C1 gene)-like 11.9928

Genes more highly expressed in primary tumors

CLDN19Claudin-1920.4327
HPRHaptoglobin-related protein11.7846
IGFBP7Insulin-like growth factor binding protein 710.6376
ZFYVE20Zinc finger FYVE domain containing 2010.4542
HPHaptoglobin9.1384
GFRA1GDNF family receptor alpha 18.6866
APOBEC2Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 28.6565
STK39Serine threonine kinase 39 (STE20/SPS1 homolog, yeast)8.0239
SLC6A16Solute carrier family 6, member 167.2568