The Role of Prophylactic Central Neck Dissection in Differentiated Thyroid Carcinoma: Issues and Controversies

Table 4

A comparison of surgical-related morbidities between those who underwent a total thyroidectomy and prophylactic neck dissection (CND+ group) and those who underwent a total thyroidectomy only (CND− group).

First author/year	Number of; Patients		Transient; hypoparathyroidism (%)		Permanent; hypoparathyroidism (%)		Transient recurrent; nerve injury (%)		Permanent recurrent; nerve injury (%)
	CND+	CND−	CND+	CND−	CND+	CND−	CND+	CND−	CND+	CND−
Henry/1998 [69]	P-50,B	50	14^#	8	4.0^#	0	4^#	6	0	0
Steinmullar/1999 [70]	P-53, B	70	39.6	35.7	0.7	0	4^#	6	0	0
Gemsenjäger/2003 [58]	P-29, A/B; T-42, B	159			P-0 T-1.4	0	3.7	8.6	1.9	0
Sywak/2006 [5]	P-56, A	391	18*	8	1.8	0.5			P-0 T-4.2	0
Roh/2007 [23]	P-40, B; T-42	73	30.5*	9.6	4.9	0	1.8	1.0	0	1
Palestini/2008 [22]	P-93, A	148	26.9*	12.8	0	2.7	7.3	4.1	3.6	2.7
Rosenbaum/2009 [27]	P-4, B; T-18, B	88	86*	58	5	0	5.4*	1.4	0	1.4
Sadowski/2009 [25]	P-169, B; T-11, A	130					9	2	0	1
Hughes/2010 [6]	P-78, B	65	27*	8	2.6	0	11	6	4	0
Moo/2010 [24]	P-45, B	36	31*	5	0	5^#	0	3.1
Shindo/2010 [21]	P-108, A; T-14, B	134	13.1	25.4*	0.8	0.7	4^#	0	0	0
Lang/2011 [8]	P-82, A	103	18.3*	8.7	2.4	1.0	0	1	0	0

*: P < 0.05, ^#: P value not reported.
Abbreviations: P: prophylactic, T: therapeutic; A: unilateral, B: bilateral.