Evaluation of Lentiviral-Mediated Expression of Sodium Iodide Symporter in Anaplastic Thyroid Cancer and the Efficacy of In Vivo Imaging and Therapy
Figure 5
In vivo 124I MicroPET imaging ARO parental cells and cells transduced with LV-CMV-hNIS were subcutaneously implanted into mice shoulder and allowed to form the tumors. When tumors reached 8 mm in size, images were taken for 30 min at 60 min after administration of 1.85 MBq (50uCi) of 124I. Images show that tumor derived from transduced ARO cells accumulates 124I more efficiently than tumor derived from ARO cells.
