Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma
Figure 1
CSC Theory. (a) Origin of CSC. CSC may originate from endogenous stem cells (SC) or reprogramming of the transit amplifying (TA) or differentiated (Diff) cell population. (b) The CSC theory proposes a tumor cell hierarchy with the CSC at the apex. Only CSCs are able to give rise to new tumors and provide support for ongoing tumor growth (Green: CSC, Red: Transit amplifying population, Pink: differentiated cell population).
