Table of Contents Author Guidelines Submit a Manuscript
Journal of Oncology
Volume 2011 (2011), Article ID 798592, 25 pages
http://dx.doi.org/10.1155/2011/798592
Research Article

Gene Expression Differences between Enriched Normal and Chronic Myelogenous Leukemia Quiescent Stem/Progenitor Cells and Correlations with Biological Abnormalities

1Mayo Clinic, Scottsdale, AZ 85259, USA
2Molecular Pharmacology & Chemistry Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA
3Department of Epidemiology-Biostatistics UCSF, San Francisco, CA 94107, USA
4Department of Epidemiology-Biostatistics, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA
5Genomics Core Laboratory, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA
6Hiberna Corporation, 1941 Pearl Street, Suite 200, Boulder, CO 80302, USA

Received 28 July 2010; Revised 17 November 2010; Accepted 7 December 2010

Academic Editor: Aurelio Lorico

Copyright © 2011 M. Affer et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [12 citations]

The following is the list of published articles that have cited the current article.

  • D Wisniewski, M Affer, J Willshire, and B Clarkson, “Further phenotypic characterization of the primitive lineage− CD34+CD38−CD90+CD45RA− hematopoietic stem cell/progenitor cell sub-population isolated from cord blood, mobilized peripheral blood and patients with chronic myelogenous leukemia,” Blood Cancer Journal, vol. 1, no. 9, pp. e36, 2011. View at Publisher · View at Google Scholar
  • Haojian Zhang, Cong Peng, Yiguo Hu, Huawei Li, Zhi Sheng, Yaoyu Chen, Con Sullivan, Jan Cerny, Lloyd Hutchinson, Anne Higgins, Patricia Miron, Xueqing Zhang, Michael A Brehm, Dongguang Li, Michael R Green, and Shaoguang Li, “The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells,” Nature Genetics, vol. 44, no. 8, pp. 861–871, 2012. View at Publisher · View at Google Scholar
  • Sukanya Suresh, Lynn McCallum, Lisa J. Crawford, Wan Hua Lu, Daniel J. Sharpe, and Alexandra E. Irvine, “The matricellular protein CCN3 regulates NOTCH1 signalling in chronic myeloid leukaemia,” Journal of Pathology, vol. 231, no. 3, pp. 378–387, 2013. View at Publisher · View at Google Scholar
  • Ronit Abir, Adina Aviram, Meora Feinmesser, Jerry Stein, Isaac Yaniv, Doris Parnes, Avi Ben-Haroush, Dror Meirow, Esther Rabizadeh, and Benjamin Fisch, “Ovarian minimal residual disease in chronic myeloid leukaemia,” Reproductive BioMedicine Online, 2013. View at Publisher · View at Google Scholar
  • V Tomiatti, R Istvánffy, E Pietschmann, S Kratzat, A Hoellein, L Quintanilla-Fend, N von Bubnoff, C Peschel, R A J Oostendorp, and U Keller, “Cks1 is a critical regulator of hematopoietic stem cell quiescence and cycling, operating upstream of Cdk inhibitors,” Oncogene, vol. 34, no. 33, pp. 4347–4357, 2014. View at Publisher · View at Google Scholar
  • Michaela Bayerlová, Klaus Jung, Frank Kramer, Florian Klemm, Annalen Bleckmann, and Tim Beißbarth, “Comparative study on gene set and pathway topology-based enrichment methods,” BMC Bioinformatics, vol. 16, no. 1, 2015. View at Publisher · View at Google Scholar
  • Jaspal Kaeda, Frauke Ringel, Christian Oberender, Ken Mills, Concetta Quintarelli, Fabrizio Pane, Steffen Koschmieder, Robert Slany, Rolf Schwarzer, Giuseppe Saglio, Philipp Hemmati, Antje van Lessen, Leila Amini, Martin Gresse, Elisabetta Vagge, Thomas Burmeister, Anna Serra, Anne Carson, Michaela Schwarz, Jörg Westermann, Franziska Jundt, Bernd Dörken, and Philipp le Coutre, “ Up-regulated MSI2 is associated with more aggressive chronic myeloid leukemia ,” Leukemia & Lymphoma, pp. 1–9, 2015. View at Publisher · View at Google Scholar
  • Fengfeng Wang, William C. S. Cho, Lawrence W. C. Chan, S. C. Cesar Wong, Nancy B. Y. Tsui, Parco M. Siu, S. P. Yip, and Benjamin Y. M. Yung, “Gene Network Exploration of Crosstalk between Apoptosis and Autophagy in Chronic Myelogenous Leukemia,” BioMed Research International, vol. 2015, pp. 1–9, 2015. View at Publisher · View at Google Scholar
  • Nataliia V. Guz, Sapan J. Patel, Maxim E. Dokukin, Bayard Clarkson, and Igor Sokolov, “Biophysical Differences between Chronic Myelogenous Leukemic Quiescent and Proliferating Stem/Progenitor Cells,” Nanomedicine: Nanotechnology, Biology and Medicine, 2016. View at Publisher · View at Google Scholar
  • Sheela A. Abraham, Lisa E. M. Hopcroft, Emma Carrick, Mark E. Drotar, Karen Dunn, Andrew J. K. Williamson, Koorosh Korfi, Pablo Baquero, Laura E. Park, Mary T. Scott, Francesca Pellicano, Andrew Pierce, Mhairi Copland, Craig Nourse, Sean M. Grimmond, David Vetrie, Anthony D. Whetton, and Tessa L. Holyoake, “Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells,” Nature, 2016. View at Publisher · View at Google Scholar
  • Anuradha Tarafdar, Lisa E. M. Hopcroft, Paolo Gallipoli, Francesca Pellicano, Jennifer Cassels, Alan Hair, Koorosh Korfi, Heather G. Jørgensen, David Vetrie, Tessa L. Holyoake, and Alison M. Michie, “CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression,” Blood, vol. 129, no. 2, pp. 199–208, 2016. View at Publisher · View at Google Scholar
  • Xuye Yuan, Jiajia Chen, Yin Li, Luonan Chen, Haiying Hua, Yuxin Lin, Lihua Xu, and Bairong Shen, “Network biomarkers constructed from gene expression and protein-protein interaction data for accurate prediction of leukemia,” Journal of Cancer, vol. 8, no. 2, pp. 278–286, 2017. View at Publisher · View at Google Scholar