Research Article
A Cohort Study of p53 Mutations and Protein Accumulation in Benign Breast Tissue and Subsequent Breast Cancer Risk
Table 1
Number of cases and controls by center and exclusions.
| | London | Portland | Total |
| Number of unique individuals | 452 | 613 | 1065 | (i) Number of controls used an additional 1× | 0 | 7 | | (ii) Number of controls used an additional 2× | 0 | 3 | | (iii) Number of controls that reappear as cases | 8 | 6 | |
| Total number of records | 460 | 632 | 1092 | (i) Number of case records | 230 | 316 | 546 | (ii) Number of control records | 230 | 316 | 546 |
| Exclusions (breast cancer before baseline, no breast tissue, missing pathology data) | 128 | 2 | 130 | (i) Cases records excluded | 53 | 2 | 55 | (ii) Control records excluded | 75 | 0 | 75 |
| Total number of records after exclusions (used in unmatched analysis) | 332 | 630 | 962 | (i) Cases after exclusions | 177 | 314 | 491 | (ii) Controls after exclusions | 155 | 316 | 471 | Total number of women after exclusions | 326 | 611 | 937 | Total number of case-control sets (used in matched analysis) | 1481 | 3161 | 464 |
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Matched pairs only.
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