Review Article

Adrenocortical Carcinoma: Current Therapeutic State-of-the-Art

Table 3

Summary of series of laparoscopic adrenalectomies for adrenal malignancies.

AuthorTotal number of LATotal number of malignant casesMean tumor size (cm)Duration of followup (months)Recurrence rateComments

Henry et al., 2002 [24]2336 ACC7.44717%1 dead of disease
Porpiglia et al., 2004 [25]2056 ACC6.9300%1 dead of cerebrovascular accident
Corcione et al., 2005 [26]1002 ACC8.513.650%Both patients alive, one has still disease
Gonzalez et al., 2005ā€‰ā€‰[19]6 6 ACC 5.3 28 100% 2 are still alive with disease, remaining 4 died of disease
Palazzo et al., 2006 [27]3913 MP6.83433%1 dead of disease
Lombardi et al., 2006 [28]794 ACC
3 MP
5.92329%4 alive disease free, 2 alive with disease and one dead of liver failure
Liao et al., 2006 [29]2104 ACC6.2 3925%1 alive disease free, 1 alive with disease and 2 died of disease
Nocca et al., 2007 [30]1314 ACC8.53425%3 alive disease free, 1 died of metastatic disease
Ramacciato et al., 2008 [31]182 ACC8.3440%Alive and disease free
Brix et al., 2010 [32]3535 ACC6.23977%37% of patients died from ACC
Miller et al., 2010 [33]17177.03620%Not investigated, but authors concluded that the mean time to local recurrence was shorter in LA compared to the open group

ACC: adrenocortical cancer; MP: malignant pheochromocytoma; LA: laparoscopic adrenalectomy.