<i>In Vivo</i> Time-Course Imaging of Tumor Angiogenesis in Colorectal Liver Metastases in the Same Living Mice Using Two-Photon Laser Scanning Microscopy

<table>Imaging of early events of colorectal liver metastasis by intravital TPLSM. (a) Normal liver. (b) Arrest of a tumor cell in the hepatic sinusoid (2 hours after inoculation). (c) Tumor-cell-induced platelet aggregation (white arrows, 2 hours after inoculation). (d) Phagocytosis by a Kupffer cell (24 hours after inoculation). (e) Phagocytosis by a Kupffer cell at different depth. (f) Extravasation of a tumor cell (24 hours after inoculation) (bar, 50 <i>μ</i>m).</table>

Journal of Oncology

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Figure 3: <i>In Vivo</i> Time-Course Imaging of Tumor Angiogenesis in Colorectal Liver Metastases in the Same Living Mice Using Two-Photon Laser Scanning Microscopy 

Figure 3 | In Vivo Time-Course Imaging of Tumor Angiogenesis in Colorectal Liver Metastases in the Same Living Mice Using Two-Photon Laser Scanning Microscopy 