Rapid Stereomicroscopic Imaging of HER2 Overexpression in Ex Vivo Breast Tissue Using Topically Applied Silica-Based Gold Nanoshells
Figure 3
Darkfield images of HER2-positive tissue sectioned after incubation with anti-HER2-targeted silica-gold nanoshells. (a) Surface of HER2-positive tissue, (b) 24 μm beyond the surface of the same tissue. (c) Scattering spectra of the fields of view depicted in (a) and (b). Additionally, spectra from the surface of HER2-positive tissue not incubated with silica-gold nanoshells are shown as a negative control. Scale bar = 50 μm.
