Rapid Stereomicroscopic Imaging of HER2 Overexpression in Ex Vivo Breast Tissue Using Topically Applied Silica-Based Gold Nanoshells
Figure 4
Raw stereomicroscope images of (a) and (b) HER2-overexpressing cancerous and (c) normal tissue incubated with either buffer or HER2-targeted nanoshells for 5 minutes at 37°C. Cancerous tissue taken from a patient (a) without chemotherapy and (b) following neoadjuvant chemotherapy. Arrows represent nanoshells. Images taken at 2x. Scale bars = 2.5 mm.