Research Article
Definitive Radiotherapy versus Postoperative Radiotherapy of Patients with Oro- and Hypopharyngeal Cancer: Impact of Prognostic Factors
Table 1
Patient characteristics.
| Characteristics | Definitive RT | Postoperative RT | | % | | % |
| Gender | | | | | Female | 17 | 10.5 | 19 | 15.1 | Male | 145 | 89.5 | 107 | 84.9 | Age (years) | | | | | ≤56 | 87 | 53.7 | 72 | 57.1 | >56 | 75 | 46.3 | 54 | 42.9 | Hemoglobin level pre-RT (g/dL) | | | | | ≤12 | 27 | 17.6 | 46 | 42.6 | >12 | 126 | 82.4 | 62 | 57.4 | Tumor site | | | | | Oropharynx | 95 | 58.6 | 68 | 54.0 | Hypopharynx | 67 | 41.4 | 58 | 46.0 | cT-Classification# | | | | | 1, 2 | 13 | 8.1 | 66 | 52.4 | 3, 4 | 148 | 91.9 | 60 | 47.6 | cN-Classification# | | | | | 0, 1 | 14 | 3.7 | 50 | 39.7 | 2, 3 | 148 | 91.3 | 76 | 60.3 | Stage | | | | | ≤3 | 4 | 3.1 | 42 | 33.3 | 4 | 157 | 96.9 | 84 | 66.7 | Total tumor volume | | | | | ≤median* | 52 | 43.0 | 52 | 46.8 | >median* | 69 | 57.0 | 59 | 53.2 | R-Classification | | | | | 0 | — | — | 78 | 65.0 | 1 | — | — | 37 | 30.8 | 2 | — | — | 5 | 4.2 | Fractionation regimen | | | | | Conventional | 24 | 14.8 | 126 | 100.0 | Concomitant boost | 138 | 85.2 | 0 | 0.0 | Simultaneous radiochemotherapy | | | | | Yes | 99 | 61.1 | 0 | 0.0 | No | 63 | 38.9 | 126 | 100.0 | RT interruptions >5 days | | | | | Yes | 36 | 22.2 | 24 | 20.0 | No | 126 | 77.8 | 96 | 80.0 | Interval surgery-RT >32 days | | | | | Yes | — | — | 58 | 47.5 | No | — | — | 64 | 52.5 |
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RT, radiation therapy; *median for definitive RT is 69.4 cm3, median for postoperative RT is 21.2 cm3.
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