Journal of Oncology / 2012 / Article / Fig 5

Clinical Study

Salivary Protein Profiles among HER2/neu-Receptor-Positive and -Negative Breast Cancer Patients: Support for Using Salivary Protein Profiles for Modeling Breast Cancer Progression

Figure 5

It illustrates the presence of profilin-1 in the SKBR3 and HSG cell lysates and saliva sampled from healthy, benign, and malignant tumor patients. Profilin is a downregulated protein in the presence of malignancy, and it is visualized by the lighter bands associated with malignancy. It is also worth noting that the Her2/neu-receptor-negative band is darker than the Her2/neu-receptor-positive counterpart suggesting further downregulation of the profiling-1 protein.
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